منابع مشابه
Bacteriophage Assembly
Bacteriophages have been a model system to study assembly processes for over half a century. Formation of infectious phage particles involves specific protein-protein and protein-nucleic acid interactions, as well as large conformational changes of assembly precursors. The sequence and molecular mechanisms of phage assembly have been elucidated by a variety of methods. Differences and similarit...
متن کاملAssembly of bacteriophage into functional materials.
For the last decade, the fabrication of ordered structures of phage has been of great interest as a means of utilizing the outstanding biochemical properties of phage in developing useful materials. Combined with other organic/inorganic substances, it has been demonstrated that phage is a superior building block for fabricating various functional devices, such as the electrode in lithium-ion ba...
متن کاملGenetic basis of bacteriophage HK97 prohead assembly.
We report studies to determine which bacteriophage genes are required for assembly of phage HK97 proheads and what roles they play. We identify the gene encoding the major capsid protein of phage HK97 and report its DNA sequence, together with the DNA sequences of the two genes immediately upstream from it. When the capsid protein is expressed from a plasmid in the absence of other phage-encode...
متن کاملIn vitro assembly of bacteriophage Lambda heads.
The assembly of plaque-forming particles in cell-free extracts of induced lambda lysogens was observed two ways. (i) DNA isolated from a lambda-related phage, 434 for example, is added to an extract of an induced lambda lysogen, and plaque-formers with the genotype of the added DNA are detected. (ii) One extract from an induced lambda lysogen that carries an amber mutation in one of the head ge...
متن کاملStructural Studies of Bacteriophage a3 Assembly
Department of Veterinary Science and Microbiology University of Arizona Building 90, Room 201, Tucson AZ 85721, USA Bacteriophage a3 is a member of the Microviridae, a family of small, singlestranded, icosahedral phages that include fX174. These viruses have an ssDNA genome associated with approximately 12 copies of an H pilot protein and 60 copies of a small J DNA-binding protein. The surround...
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ژورنال
عنوان ژورنال: Viruses
سال: 2011
ISSN: 1999-4915
DOI: 10.3390/v3030172